Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ORF8 Protein of SARS-CoV-2 Modulates the Spike Protein and Its Implications in Viral Transmission

19 May 2022

Abstract excerpt

COVID-19 is currently global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Accompanying the rapid spread of the error-prone RNA-based genome, several dominant SARS-CoV-2 variants have been genetically identified. The mutations in the spike protein, which are essential for receptor binding and fusion, have been intensively investigated for their contributions to viral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35663899
DOI: 10.3389/fmicb.2022.883597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ORF8 Protein of SARS-CoV-2 Modulates the Spike Protein and Its Implications in Viral TransmissionPMID 35663899Read ↗

A Comprehensive Analysis of Structural and Functional Changes Induced by SARS-CoV-2 Spike Protein MutationsSemantic proximity Read ↗

SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cellsSemantic proximity Read ↗

Domains and Functions of Spike Protein in Sars-Cov-2 in the Context of Vaccine Design.Semantic proximity Read ↗

A Comprehensive Analysis of Structural and Functional Changes Induced by SARS-CoV-2 Spike Protein MutationsSemantic proximity Read ↗

Spike protein of SARS-CoV-2 variants: a brief review and practical implications.Semantic proximity Read ↗

Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variantsSemantic proximity Read ↗

Unique mutations in SARS-CoV-2 Omicron subvariants' non-spike proteins: Potential impacts on viral pathogenesis and host immune evasion.Semantic proximity Read ↗

SARS-CoV-2 Delta Spike Protein Enhances the Viral Fusogenicity and Inflammatory Cytokine ProductionSemantic proximity Read ↗

Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease.Semantic proximity Read ↗

Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variantSemantic proximity Read ↗

A Conservative Replacement in the Transmembrane Domain of SARS-CoV-2 ORF7a as a Putative Risk Factor in COVID-19Semantic proximity Read ↗

Structure-function relations of the SARS-CoV-2 spike protein and impact of mutations in the variants of concern.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.