Article

Polyclonal and monoclonal thyroid nodules coexist within human multinodular goiters

1994-07-01

Abstract excerpt

Although somatic mutations have been identified in a subset of thyroid nodules, the pathogenesis of nodules in multinodular goiters remains unclear. Clonal analysis indicates whether a nodule arises from the polyclonal proliferation of a group of cells or forms a clone from a genetically altered cell. Individual thyroid nodules have been shown to be of polyclonal or monoclonal origin. In this study we examined the...

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Thyroid Cancer Diagnosis and Treatment

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Literature Corpus work: b8dc6cba-661a-5f07-b3c2-40dd6062abbf
DOI: 10.1210/jc.79.1.134

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