Article
Clonal analysis of precancerous lesion of hepatocellular carcinoma.
Gastroenterology - 1 Aug 1996
Aihara T, Noguchi S, Sasaki Y, Nakano H, Monden M, Imaoka S
Abstract excerpt
BACKGROUND & AIMS: It remains to be established whether precancerous lesion (dysplastic nodule) of hepatocellular carcinoma (HCC) is a neoplastic or hyperplastic lesion. Clonal analysis of this lesion was conducted to elucidate this important issue on histogenesis. METHODS: The method for clonal...
Topics
- Aged
- Carcinoma, Hepatocellular
- DNA Fingerprinting
- DNA Probes
- Female
- Gene Expression Regulation, Neoplastic
- Genetic Carrier Screening
- Genetic Linkage
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Mutation
- Phosphoglycerate Kinase
- Polymorphism, Restriction Fragment Length
- Precancerous Conditions
- X Chromosome
