Article
Clonal origin of non-medullary thyroid tumours assessed by non-random X-chromosome inactivation.
European journal of endocrinology - 1 Jan 2002
Moniz Sónia, Catarino Ana L, Marques Ana R, Cavaco Branca, Sobrinho Luís, Leite Valeriano
Abstract excerpt
OBJECTIVE: X-chromosome inactivation analysis was performed in order to assess the clonal origin of non-medullary thyroid tumours and to distinguish between multicentricity and multifocality in multiple papillary thyroid carcinoma (PTC). METHODS: One hundred and thirteen tumour samples from 31 patients with isolated PTC, 16 patients with multinodular PTC, 14 patients with follicular thyroid adenoma (FTA) and 15...
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