Article

Fibronectin, DHPS and SLC3A2 Signaling Cooperate to Control Tumor Spheroid Growth, Subcellular eIF5A1/2 Distribution and CDK4/6 Inhibitor Resistance

2023-04-16

Abstract excerpt

<h4>ABSTRACT</h4> Extracellular matrix (ECM) protein expression/deposition within and stiffening of the breast cancer microenvironment facilitates disease progression and correlates with poor patient survival. However, the mechanisms by which ECM components control tumorigenic behaviors and responses to therapeutic intervention remain poorly understood. Fibronectin (FN) is a major ECM protein controlling multiple...

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Literature Corpus work: b8c0fb45-82a9-5a5f-8c7f-2ac92e1aeedd
DOI: 10.1101/2023.04.13.536765

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