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Epigenetic Alterations in Triple-Negative Breast Cancer—The Critical Role of Extracellular Matrix

9 Feb 2021

Abstract excerpt

Triple-negative breast cancer (TNBC) is an aggressive subgroup of breast cancer characterized by genomic complexity and therapeutic options limited to only standard chemotherapy. Although it has been suggested that stratifying TNBC patients by pathway-specific molecular alterations may predict benefit from specific therapeutic agents, application in routine clinical practice has not yet been established. There is...

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PMID: 33572395
DOI: 10.3390/cancers13040713

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