Article
Review of metabolic pathways activated in cancer cells as determined through isotopic labeling and network analysis.
Metabolic engineering - 1 Sept 2017
Dong Wentao, Keibler Mark A, Stephanopoulos Gregory
Abstract excerpt
Cancer metabolism has emerged as an indispensable part of contemporary cancer research. During the past 10 years, the use of stable isotopic tracers and network analysis have unveiled a number of metabolic pathways activated in cancer cells. Here, we review such pathways along with the particular tracers and labeling observations that led to the discovery of their rewiring in cancer cells. The list of such...
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