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Article

Modeling core metabolism in cancer cells: surveying the topology underlying the Warburg effect.

PloS one - 25 Aug 2010

Resendis-Antonio Osbaldo, Checa Alberto, Encarnación Sergio

Abstract excerpt

BACKGROUND: Alterations on glucose consumption and biosynthetic activity of amino acids, lipids and nucleotides are metabolic changes for sustaining cell proliferation in cancer cells. Irrevocable evidence of this fact is the Warburg effect which establishes that cancer cells prefers glycolysis over oxidative phosphorylation to generate ATP. Regulatory action over metabolic enzymes has opened a new window for...

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Identifiers

PMID: 20811631
DOI: 10.1371/journal.pone.0012383
PMCID: PMC2928278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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