Article
Cancer metabolism: key players in metabolic reprogramming.
Cancer science - 1 Mar 2013
Soga Tomoyoshi
Abstract excerpt
Over 80 years ago, Warburg discovered that cancer cells generate ATP through the glycolytic pathway, even in the presence of oxygen. The finding of this phenomenon, termed the "Warburg effect," stimulated much research on tumorigenesis, but few explanations were forthcoming to explain the observation. Recently, advanced developments in molecular biology and high-throughput molecular analyses have revealed that...
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