Article

Distinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine

2023-01-13

Abstract excerpt

<h4>Summary</h4> Drugs of abuse increase extracellular concentrations of dopamine in the nucleus accumbens (NAc), resulting in transcriptional alterations that drive long-lasting cellular and behavioral adaptations. While decades of research have focused on the transcriptional mechanisms by which drugs of abuse influence neuronal physiology and function, few studies have comprehensively defined NAc cell type hete...

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Literature Corpus work: b89dbe13-976d-517f-bf00-8827e395ad26
DOI: 10.1101/2023.01.12.523845

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