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A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens

6 Aug 2024

Abstract excerpt

Neural processing of rewarding stimuli involves several distinct regions, including the nucleus accumbens (NAc). The majority of NAc neurons are GABAergic projection neurons known as medium spiny neurons (MSNs). MSNs are broadly defined by dopamine receptor expression, but evidence suggests that a wider array of subtypes exist. To study MSN heterogeneity, we analyzed single-nucleus RNA sequencing data from the...

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PMID: 39107568
DOI: 10.1038/s41598-024-69255-0

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