Article

Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens

2025-09-11

Abstract excerpt

The nucleus accumbens (NAc) is a key component of the mesolimbic dopamine system that critically regulates many behaviors related to reward and motivation. The NAc is implicated in several neuropsychiatric disorders, including major depressive disorder, schizophrenia, and substance use disorders. Rodent studies have identified spatial organization of heterogeneous medium spiny neuron (MSN) subtypes across the NAc...

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Literature Corpus work: 5abb0253-ab75-50f1-860a-d70355fe6c1a
DOI: 10.1101/2025.09.10.675374

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