Article

<i>Chst9</i> Marks a Spatially and Transcriptionally Unique Population of <i>Oprm1</i> -Expressing Neurons in the Nucleus Accumbens

2023-10-17

Abstract excerpt

<h4>Summary</h4> Opioids produce addictive, analgesic, and euphoric effects via actions at mu opioid receptors (μORs). The μOR is encoded by the Oprm1 gene and is expressed in multiple brain regions that regulate reward and motivation, such as the nucleus accumbens (NAc). Oprm1 expression in NAc medium spiny neurons (MSNs) mediates opioid place preference, seeking, and consumption. However, recent single nucleu...

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Literature Corpus work: f3e4edb5-06a7-58a7-8ab8-43a357fdf291
DOI: 10.1101/2023.10.16.562623

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