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Single nuclei transcriptomics in human and non-human primate striatum implicates neuronal DNA damage and proinflammatory signaling in opioid use disorder

2023-05-17

Abstract excerpt

The striatum in the brain is involved in various behavioral functions, including reward, and disease processes, such as opioid use disorder (OUD). Further understanding of the role of striatal subregions in reward behaviors and their potential associations with OUD requires molecular identification of specific striatal cell types in human brain. The human striatum contains subregions based on different anatomical,...

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Literature Corpus work
319a0210-aafb-5ee6-8bfd-644033a85cc7
DOI
10.1101/2023.05.17.541145
Open publication

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Single nuclei transcriptomics in human and non-human primate striatum implicates neuronal DNA damage and proinflammatory signaling in opioid use disorderDOI 10.1101/2023.05.17.541145
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