Article
Rare and Potentially Pathogenic Variants in Hydroxycarboxylic Acid Receptor Genes Identified in Breast Cancer Cases.
2020-12-10
Abstract excerpt
<title>Abstract</title> <p><bold>Background</bold>: Three genes, clustered together on chromosome 12, comprise a group of Hydroxycarboxylic Acid Receptors (HCARs), <italic>HCAR1</italic>, <italic>HCAR2</italic>, and <italic>HCAR3</italic>. These paralogous genes encode different G-protein coupled receptors that are responsible for detecting glycolytic metabolites and controlling fatty acid oxidation. Though bette...
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Identifiers and source
- Literature Corpus work
- b89365fa-71ef-5732-8def-fb9b15f0c23b
- DOI
- 10.21203/rs.3.rs-120609/v1
