Article
Aldo-keto reductase 1C2 (AKR1C2) as the second gene associated to non-syndromic primary lipedema: investigating activating mutation or overexpression as causative factors.
European review for medical and pharmacological sciences - 1 Dec 2023
Kaftalli J, Donato K, Bonetti G, Dhuli K, Macchia A, Maltese P E, Louise Herbst K, Michelini S, Chiurazzi P, Hill M, Michelini S, Michelini S, Marceddu G, Bernini A, Bertelli M
Abstract excerpt
OBJECTIVE: Lipedema is a debilitating chronic condition predominantly affecting women, characterized by the abnormal accumulation of fat in a symmetrical, bilateral pattern in the extremities, often coinciding with hormonal imbalances. PATIENTS AND METHODS: Despite the conjectured role of sex hormones in its etiology, a definitive link has remained elusive. This study explores the case of a patient possessing a...
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