Article
Genetic polymorphisms in the human growth hormone-1 gene (GH1) and the risk of breast carcinoma.
Cancer - 15 Jul 2004
Ren Zefang, Cai Qiuyin, Shu Xiao-Ou, Cai Hui, Cheng Jia-Rong, Wen Wan-Qing, Gao Yu-Tang, Zheng Wei
Abstract excerpt
BACKGROUND: In addition to possessing many physiologic functions, human growth hormone-1 (GH1) has been shown in recent in vitro and in vivo experiments to induce malignant disease, including breast carcinoma. The authors investigated the association of breast carcinoma with genetic polymorphisms in the GH1 gene in the Shanghai Breast Cancer Study. METHODS: Included in the current investigation were 1193 women...
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