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Moxibustion Spatial Transcriptomics Reveals Aqp4 Gene Distribution and Transport to the Astrocyte Endfeet Around Lateral White Matter of Hypothalamus (LWMH) are Potential Therapeutic Targets for Cognitive Impairment in APP/PS1 Mice

2022-03-21

Abstract excerpt

<h4>Background: </h4> Aquaporin-4 ( Aqp4 ), a predominantly aquaporin expressed on astrocytic endfeet, has been found to be potential targets for lymphatic clearance and transcytotic delivery in the disorder of glial lymphatic system and white matter fluid metabolism impairment such as Alzheimer's disease (AD). Moxibustion is an experience-based effective treatment for AD. Exploring the large amount of complex dat...

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Literature Corpus work
b88790f6-5631-540f-975e-cccdcc036597
DOI
10.21203/rs.3.rs-1458363/v1
Open publication

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Moxibustion Spatial Transcriptomics Reveals Aqp4 Gene Distribution and Transport to the Astrocyte Endfeet Around Lateral White Matter of Hypothalamus (LWMH) are Potential Therapeutic Targets for Cognitive Impairment in APP/PS1 MiceDOI 10.21203/rs.3.rs-1458363/v1
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