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Article

Potential utility of aquaporin modulators for therapy of brain disorders.

Progress in brain research - 1 Jan 2008

Papadopoulos Marios C, Verkman A S

Abstract excerpt

Of the several aquaporin (AQP) water channels expressed in the central nervous system, AQP4 is an attractive target for drug discovery. AQP4 is expressed in astroglia, most strongly at the blood-brain and brain-cerebrospinal fluid barriers. Phenotype analysis of AQP4 knockout mice indicates the involvement of AQP4 in three distinct processes: brain water balance, astroglial cell migration and neural signal...

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Source

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Identifiers

PMID: 18655912
DOI: 10.1016/S0079-6123(08)00446-9
PMCID: PMC3601944

Genes

AQP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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