Article

Evaluation of gliovascular functions of Aqp4 readthrough isoforms

2023-07-25

Abstract excerpt

Aquaporin-4 (AQP4) is a water channel protein that links astrocytic endfeet to the blood-brain barrier (BBB) and regulates water and potassium homeostasis in the brain, as well as the glymphatic clearance of waste products that would otherwise potentiate neurological diseases. Recently, translational readthrough was shown to generate a C-terminally extended variant of AQP4, known as AQP4x, that preferentially loca...

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Literature Corpus work: a2f36b19-9a40-5ace-86f6-bacb0c80e207
DOI: 10.1101/2023.07.21.549379

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