Article

Understanding PITX2-dependent Atrial Fibrillation Mechanisms through Computational Models

2021-06-22

Abstract excerpt

Atrial fibrillation (AF) is a common arrhythmia. Better prevention and treatment of AF are needed to reduce AF-associated morbidity and mortality. Several major mechanisms cause AF in patients, including a genetic predisposition to develop AF. Genome-wide association studies have identified genetic variants associated with AF populations, with the strongest hits clustering on chromosome 4q25, close to the gene cod...

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Literature Corpus work: b863b507-b5ca-5115-95d7-7a3a383ea8bc
DOI: 10.20944/preprints202106.0541.v1

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