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Article

Understanding PITX2-Dependent Atrial Fibrillation Mechanisms through Computational Models.

International journal of molecular sciences - 19 Jul 2021

Bai Jieyun, Lu Yaosheng, Zhu Yijie, Wang Huijin, Yin Dechun, Zhang Henggui, Franco Diego, Zhao Jichao

Abstract excerpt

Atrial fibrillation (AF) is a common arrhythmia. Better prevention and treatment of AF are needed to reduce AF-associated morbidity and mortality. Several major mechanisms cause AF in patients, including genetic predispositions to AF development. Genome-wide association studies have identified a number of genetic variants in association with AF populations, with the strongest hits clustering on chromosome 4q25,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34299303
DOI: 10.3390/ijms22147681
PMCID: PMC8307824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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