Article

Adjusting for medication status in genome-wide association studies

2024-02-20

Abstract excerpt

When conducting genome-wide association studies, improper handling of medication status that is relevant to the trait of interest can induce biases by opening up different pathways that distort estimates of the true effect. Here, we propose the genetic empirical medication reduction adjustment (GEMRA) method which uses a heuristic search for an empirical adjustment to be applied to phenotypic values of participant...

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Literature Corpus work: b8501416-bf85-5720-a9cd-b09b0101966e
DOI: 10.1101/2024.02.19.24303028

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