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Article

Mapping the Pharmacogenetic Landscape in a Ugandan Population: Implications for Personalized Medicine in an Underrepresented Population.

Clinical pharmacology and therapeutics - 1 Oct 2024

Samarasinghe Sumudu Rangika, Lee Seung-Been, Corpas Manuel, Fatumo Segun, Guchelaar Henk-Jan, Nagaraj Shivashankar H

Abstract excerpt

Africans are extremely underrepresented in global genomic research. African populations face high burdens of communicable and non-communicable diseases and experience widespread polypharmacy. As population-specific genetic studies are crucial to understanding unique genetic profiles and optimizing treatments to reduce medication-related complications in this diverse population, the present study aims to...

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Source

Identifiers

PMID: 38837390
DOI: 10.1002/cpt.3309

Genes

CYP2B6
CYP3A5
CFTR
CYP2C19
CYP2C9
DPYD
IFNL3
SLCO1B1
TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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