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Article

A critical appraisal of pharmacogenetic inference.

Clinical genetics - 1 Mar 2018

Smit R A J, Noordam R, le Cessie S, Trompet S, Jukema J W

Abstract excerpt

In essence, pharmacogenetic research is aimed at discovering variants of importance to gene-treatment interaction. However, epidemiological studies are rarely set up with this goal in mind. It is therefore of great importance that researchers clearly communicate which assumptions they have had to make, and which inherent limitations apply to the interpretation of their results. This review discusses...

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PMID: 29136278
DOI: 10.1111/cge.13178

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