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Integrated single-cell and bulk RNA-seq analysis reveals a novel T-cell signature for prognosis and treatment response in colorectal cancer

2024-04-05

Abstract excerpt

<title>Abstract</title> <p>Colorectal cancer (CRC) is a major contributor to global morbidity and mortality, necessitating more effective therapeutic approaches. T cells, prominent in the tumor microenvironment, exert a crucial role in modulating immunotherapeutic responses and clinical outcomes in CRC. This study introduces a pioneering method for characterizing the CRC immune microenvironment using single-cell...

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Literature Corpus work
53b561eb-3459-50be-9551-db5c1a298955
DOI
10.21203/rs.3.rs-4156323/v1
Open publication

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Integrated single-cell and bulk RNA-seq analysis reveals a novel T-cell signature for prognosis and treatment response in colorectal cancerDOI 10.21203/rs.3.rs-4156323/v1
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