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Beyond Natural Antibodies: Scaffold-Based Generation of Novel Anti-3CL <sup>pro</sup> Nanobody Nb01

2025-05-07

Abstract excerpt

In the post-pandemic era, continuous mutations and persistent infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pose a significant threat to global health, making the normalization of preventive measures imperative. Due to its high conservation, the 3CLpro is relatively stable across all these variants without significant changes, suggesting that drugs targeting this enzyme could be effect...

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Literature Corpus work
b8325b13-6c36-5053-9f51-9d2ebe828522
DOI
10.1101/2025.05.06.652338
Open publication

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Beyond Natural Antibodies: Scaffold-Based Generation of Novel Anti-3CL <sup>pro</sup> Nanobody Nb01DOI 10.1101/2025.05.06.652338
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