Article

Nanobody engineering for SARS-CoV-2 neutralization and detection

2022-09-14

Abstract excerpt

In response to the ongoing SARS-CoV-2 pandemic, the quest for coronavirus inhibitors has inspired research on a variety of small proteins beyond conventional antibodies, including robust single-domain antibody fragments, ‘nanobodies’. Here, we explore the potential of nanobody engineering in the development of antivirals and diagnostic tools. Through fusion of nanobody domains that target distinct binding sites, w...

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Literature Corpus work: b3785880-26db-5ada-aa16-80c14c2b76c8
DOI: 10.1101/2022.09.14.507920

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