Article

<i>Llamanade</i> : an open-source computational pipeline for robust nanobody humanization

2021-08-04

Abstract excerpt

Nanobodies (Nbs) have recently emerged as a promising class of antibody fragments for biomedical and therapeutic applications. Despite having marked physicochemical properties, Nbs are derived from camelids and may require “humanization” to improve translational potentials for clinical trials. Here we have systematically analyzed the sequence and structural properties of Nbs based on NGS (next-generation sequencin...

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Literature Corpus work: 797c74db-1991-5b65-b370-f3f9ef36b4e8
DOI: 10.1101/2021.08.03.455003

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