Article

The formyl peptide receptor 2 regulates microglial phenotype through immunometabolism : implications for Alzheimer's disease

2019-01-01

Abstract excerpt

Microglia are key players in the pathology of Alzheimer’s disease (AD), driving chronic inflammation, oxidative stress, and the altered metabolism seen in the brains of patients. With clinical trials continuing to fail, new approaches towards drug development are critical. Strategies to reduce microglial activation may therefore be a viable therapeutic approach to tackling AD. Formyl peptide receptor 2 (Fpr2), whi...

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Literature Corpus work: b8228856-1ca2-5211-984e-ba8b5fe1a220
DOI: 10.34737/qy292

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