Back to search

Article

Optical microscopy reveals the dynamic nature of <i>B. pseudomallei</i> morphology during β-lactam antimicrobial susceptibility testing

2020-01-14

Abstract excerpt

<h4>Background</h4> In Gram-negative species, β-lactam antibiotics target penicillin binding proteins (PBPs) resulting in morphological alterations of bacterial cells. Observations of antibiotic-induced cell morphology changes can rapidly and accurately differentiate drug susceptible from resistant bacterial strains; however, resistant cells do not always remain unchanged. Burkholderia pseudomallei is a Gram-neg...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b8171274-1c8d-5d1d-b9a4-8f17697e692a
DOI
10.1101/2020.01.13.904995
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Optical microscopy reveals the dynamic nature of <i>B. pseudomallei</i> morphology during β-lactam antimicrobial susceptibility testingDOI 10.1101/2020.01.13.904995
Image-Based Dynamic Phenotyping Reveals Genetic Determinants of Filamentation-Mediated β-Lactam ToleranceSemantic proximity
IscR-mediated morphological regulation confers virulence and stress resistance by reducing stress molecule uptake in <i>Acinetobacter baumannii</i>Semantic proximity
<i>Burkholderia pseudomallei</i> BicA protein promotes pathogenicity in macrophages by regulating Invasion, Intracellular Survival, and VirulenceSemantic proximity
Effect of colony morphology variation of Burkholderia pseudomallei on intracellular survival and resistance to antimicrobial environments in human macrophages in vitroSemantic proximity
Pathogenicity and virulence ofBurkholderia pseudomalleiSemantic proximity
Burkholderia pseudomallei transcriptional adaptation in macrophagesSemantic proximity
Raising the stakes: Loss of efflux-pump regulation decreases meropenem susceptibility in <i>Burkholderia pseudomallei</i>Semantic proximity
Mechanisms of Antibiotic Resistance in <i>Burkholderia Pseudomallei</i> : Implications for Treatment of MelioidosisSemantic proximity
Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen Burkholderia pseudomallei K96243.Semantic proximity
Adaptation and Antibiotic Tolerance of Anaerobic Burkholderia pseudomalleiSemantic proximity
Genomic comparison and phenotypic profiling of small colony variants of Burkholderia pseudomallei.Semantic proximity
Biological relevance of colony morphology and phenotypic switching by Burkholderia pseudomallei.Semantic proximity
Select a neighboring publication to make it the new centre.