Article
Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen Burkholderia pseudomallei K96243.
PloS one - 22 Dec 2010
Dowling Andrea J, Wilkinson Paul A, Holden Matthew T G, Quail Michael A, Bentley Stephen D, Reger Julia, Waterfield Nicholas R, Titball Richard W, Ffrench-Constant Richard H
Abstract excerpt
Burkholderia pseudomallei is an important human pathogen whose infection biology is still poorly understood. The bacterium is endemic to tropical regions, including South East Asia and Northern Australia, where it causes melioidosis, a serious disease associated with both high mortality and antibiotic resistance. B. pseudomallei is a Gram-negative facultative intracellular pathogen that is able to replicate in...
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