Article
Adaptation and Antibiotic Tolerance of Anaerobic Burkholderia pseudomallei
2 May 2011
Abstract excerpt
The Gram-negative bacterium Burkholderia pseudomallei is the etiological agent of melioidosis and is remarkably resistant to most classes of antibacterials. Even after months of treatment with antibacterials that are relatively effective in vitro, there is a high rate of treatment failure, indicating that this pathogen alters its patterns of antibacterial susceptibility in response to cues encountered in the...
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