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Dietary molybdenum cofactor promotes fitness by increasing Moco content and sulfite oxidase activity in the nematode <i>C. elegans</i>

2022-08-31

Abstract excerpt

Molybdenum cofactor (Moco) is a prosthetic group necessary for the activity of 4 unique enzymes, including the essential sulfite oxidase (SUOX-1). Moco is required for life; humans with inactivating mutations in the genes encoding Moco-biosynthetic enzymes display Moco deficiency, a rare and lethal inborn error of metabolism. Despite its importance to human health, little is known about how Moco moves among and be...

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Literature Corpus work
b7ab4740-6697-5a15-b273-db9057153c74
DOI
10.1101/2022.08.31.506081
Open publication

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