Article

Heme’s relevance genuine? Re-visiting the roles of TANGO2 homologs including HRG-9 and HRG-10 in <i>C. elegans</i>

2023-11-30

Abstract excerpt

Mutations in the TANGO2 gene are associated with a severe neurometabolic disorder in humans, often presenting with life-threatening metabolic crisis. However, the function of TANGO2 protein remains unknown. It has recently been proposed that TANGO2 transports heme within and between cells, from areas with high heme concentrations to those with lower concentrations. Here, we demonstrate that prior heme-related obs...

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Literature Corpus work: e3457c1c-0d26-5320-8649-180c798ce96f
DOI: 10.1101/2023.11.29.569072

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