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Article

Insights gained from modelling high‐grade glioma in the mouse

28 Oct 2011

Abstract excerpt

High-grade gliomas (HGGs) are devastating primary brain tumours with poor outcomes. Advances towards effective treatments require improved understanding of pathogenesis and relevant model systems for preclinical testing. Mouse models for HGG provide physiologically relevant experimental systems for analysis of HGG pathogenesis. There are advantages and disadvantages to the different methodologies used to generate...

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PMID: 22035336
DOI: 10.1111/j.1365-2990.2011.01231.x

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