Article
Contemporary Mouse Models in Glioma Research.
Cells - 23 Mar 2021
Hicks William H, Bird Cylaina E, Traylor Jeffrey I, Shi Diana D, El Ahmadieh Tarek Y, Richardson Timothy E, McBrayer Samuel K, Abdullah Kalil G
Abstract excerpt
Despite advances in understanding of the molecular pathogenesis of glioma, outcomes remain dismal. Developing successful treatments for glioma requires faithful in vivo disease modeling and rigorous preclinical testing. Murine models, including xenograft, syngeneic, and genetically engineered models, are used to study glioma-genesis, identify methods of tumor progression, and test novel treatment strategies....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.