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Article

Genetic modeling of gliomas in mice: new tools to tackle old problems.

Glia - 1 Aug 2011

Hambardzumyan Dolores, Parada Luis F, Holland Eric C, Charest Al

Abstract excerpt

The recently published comprehensive profiles of genomic alterations in glioma have led to a refinement in our understanding of the molecular events that underlie this cancer. Using state-of-the-art genomic tools, several laboratories have created and characterized accurate genetically engineered mouse models of glioma based on specific genetic alterations observed in human tumors. These in vivo brain tumor...

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Source

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Identifiers

PMID: 21305617
DOI: 10.1002/glia.21142
PMCID: PMC3619979

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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