Article

sSNAPPY: an R/Bioconductor package for single-sample directional pathway perturbation analysis

2024-06-13

Abstract excerpt

A common outcome of analysing RNA-Seq data is the detection of biological pathways with significantly altered activity between the conditions under investigation. Whilst many strategies test for over-representation of genes, showing changed expression within pre-defined gene-sets, these analyses typically do not account for gene-gene interactions encoded by pathway topologies, and are not able to directly predict...

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Literature Corpus work: b799d17d-fc18-5f48-95c8-fddd6dd7c2ee
DOI: 10.12688/f1000research.149494.1

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