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Senescent Stroma-Derived Glutamine: A Driver of Aggressiveness in Prostate and Ovarian Cancer Cells

2026-03-03

Abstract excerpt

Cancer progression is influenced by the dynamic interplay between tumor cells and the surrounding stromal microenvironment. Therapy-induced senescence (TIS) of stromal fibroblasts represents a common outcome of anticancer treatments, contributing to tumor progression through the senescence-associated secretory phenotype (SASP). While SASP cytokines promote cancer malignancy, the contribution of secreted metabolite...

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Literature Corpus work
b7956037-48a5-5e75-9e6c-62f54789cb8e
DOI
10.20944/preprints202603.0284.v1
Open publication

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Senescent Stroma-Derived Glutamine: A Driver of Aggressiveness in Prostate and Ovarian Cancer CellsDOI 10.20944/preprints202603.0284.v1
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