Article

SH3BP2 Deficiency Ameliorates Murine Systemic Lupus Erythematosus

2020-09-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The adaptor protein Src homology 3 domain-binding protein 2 (SH3BP2) is widely expressed in immune cells, such as myeloid cells, B cells, and T cells. It controls intracellular signaling pathways, including Syk and Src. The present study was undertaken to investigate the role of SH3BP2 in a murine systemic lupus erythematosus model.<bold>Methods:</bold> For the...

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Literature Corpus work: b77cefeb-c267-587b-93cc-9d04af71102d
DOI: 10.21203/rs.3.rs-74861/v1

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