Article

Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals

2018-08-03

Abstract excerpt

<h4>ABSTRACT</h4> Back pain (BP) is a common condition of major social importance and poorly understood pathogenesis. Combining data from the UK Biobank and CHARGE consortium cohorts allowed us to perform a very large GWAS (total N = 509,070) and examine the genetic correlation and pleiotropy between BP and its clinical and psychosocial risk factors. We identified and replicated three BP associated loci, includin...

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Literature Corpus work: b77b6426-cb4c-54bd-84f3-8aea015abbf5
DOI: 10.1101/384255

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