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Article

Sex- and age-specific genetic analysis of chronic back pain.

Pain - 1 Apr 2021

Freidin Maxim B, Tsepilov Yakov A, Stanaway Ian B, Meng Weihua, Hayward Caroline, Smith Blair H, Khoury Samar, Parisien Marc, Bortsov Andrey, Diatchenko Luda, Børte Sigrid, Winsvold Bendik S, Brumpton Ben M, Zwart John-Anker, Aulchenko Yurii S, Suri Pradeep, Williams Frances M K

Abstract excerpt

ABSTRACT: Sex differences for chronic back pain (cBP) have been reported, with females usually exhibiting greater morbidity, severity, and poorer response to treatment. Genetic factors acting in an age-specific manner have been implicated but never comprehensively explored. We performed sex- and age-stratified genome-wide association study and single nucleotide polymorphism-by-sex interaction analysis for cBP...

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Source

Identifiers

PMID: 33021770
DOI: 10.1097/j.pain.0000000000002100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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