Article

A shared genetic signature for common chronic pain conditions and its impact on biopsychosocial traits

2022-03-14

Abstract excerpt

The multifactorial nature of chronic pain with its numerous comorbidities presents a formidable challenge in disentangling their aetiology. Here, we performed genome-wide association studies of eight regional chronic pain types using UK Biobank data (N=4,037–79,089 cases; N=239,125 controls), followed by bivariate linkage disequilibrium-score regression and latent causal variable analyses to determine (respectivel...

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Literature Corpus work: 35d83628-628b-5baf-9c2e-3d9ae95bd99a
DOI: 10.1101/2022.03.13.22272317

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