Article

Negative screening for 12 rare LRRK2 pathogenic variants in a cohort of Nigerians with Parkinson’s disease

2020-07-01

Abstract excerpt

Mutations in the leucine-rich repeat kinase 2 ( LRRK2 ) gene are the most commonly identified genetic variants in familial and sporadic Parkinson’s disease (PD). Over three hundred LRRK2 variants have been described in the literature, of which at least 17 have a confirmed or probable pathogenic role in PD. The distribution of these rare pathogenic variants has been shown to be different among ethnic groups inclu...

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Literature Corpus work: b75b712d-6220-5158-b631-a3a7091ac4b0
DOI: 10.1101/2020.06.30.179739

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