Article
Absence of commonly reported leucine-rich repeat kinase 2 mutations in Eastern Indian Parkinson's disease patients.
Genetic testing and molecular biomarkers - 1 Oct 2010
Sanyal Jaya, Sarkar Biswanath, Ojha Sabyasachi, Banerjee Tapas Kumar, Ray Bidhan Chandra, Rao Vadlam Raghavendra
Abstract excerpt
BACKGROUND: Pathogenic mutations in leucine-rich repeat kinase 2 (LRRK2; PARK8) encoding dardarin, implicated in patients with autosomal dominant and sporadic Parkinson's disease (PD) among different ethnic groups (Ashkenazi Jews, North African Arabs, Basques) might be of some help in diagnostic screening and genetic counseling. AIM OF THE STUDY: We investigated the seven common mutations spanning exons 31, 35,...
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