Article

Melanocortin system activates carotid body arterial chemoreceptors in hypertension

2024-07-25

Abstract excerpt

<h4>Background</h4> The body’s internal milieu is controlled by a system of interoceptors coupled to motor outflows that drive compensatory adaptive responses. These include the arterial chemoreceptors, best known for sensing arterial oxygen. In cardiometabolic diseases, such as essential hypertension, the carotid bodies (CB) exhibit heightened reflex sensitivity and tonic activity without an apparent stimulus. T...

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Literature Corpus work: b724b030-89c0-5147-a3f9-4ea06302754e
DOI: 10.1101/2024.07.22.604704

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