Article
The molecular basis of blood pressure variation.
Pediatric nephrology (Berlin, Germany) - 1 Mar 2013
Toka Hakan R, Koshy Jacob M, Hariri Ali
Abstract excerpt
Advances in genetic mapping and sequencing techniques have led to substantial progress in the study of rare monogenic (Mendelian) forms of abnormal blood pressure. Many disease-defining pathways for hypertension have been identified in the past two decades. Perturbations in renal salt handling appear to be a common mechanism underlying these rare syndromes of hypertension. Excess activation at various points in...
Topics
- Animals
- Blood Pressure
- Genetic Predisposition to Disease
- Humans
- Hypertension
- Hypotension
- Kidney
- Phenotype
- Prognosis
- Renal Tubular Transport, Inborn Errors