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Article

Sympathetic function in human carriers of melanocortin-4 receptor gene mutations.

The Journal of clinical endocrinology and metabolism - 1 Apr 2010

Sayk Friedhelm, Heutling Dennis, Dodt Christoph, Iwen K Alexander, Wellhoner J Peter, Scherag Susann, Hinney Anke, Hebebrand Johannes, Lehnert Hendrik

Abstract excerpt

CONTEXT: Melanocortinergic pathways clearly appear to be involved in obesity-associated sympathetic overactivity and its hemodynamic and thermoregulatory consequences. Individuals with dysfunctional mutations in the melanocortin-4 receptor gene (MC4R) are subject to obesity without developing hyp...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20147580
DOI: 10.1210/jc.2009-2297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20147580-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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