Article
Afferent Baroreflex Dysfunction: Decreased or Excessive Signaling Results in Distinct Phenotypes.
Seminars in neurology - 1 Oct 2020
Norcliffe-Kaufmann Lucy, Millar Vernetti Patricio, Palma Jose-Alberto, Balgobin Bhumika J, Kaufmann Horacio
Abstract excerpt
Head and neck tumors can affect afferent baroreceptor neurons and either interrupt or intermittently increase their signaling, causing blood pressure to become erratic. When the afferent fibers of the baroreflex are injured by surgery or radiotherapy or fail to develop as in familial dysautonomia, their sensory information is no longer present to regulate arterial blood pressure, resulting in afferent baroreflex...
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